Impact of bleeding on mortality after percutaneous coronary intervention results from a patient-level pooled analysis of the REPLACE-2 (randomized evaluation of PCI linking angiomax to reduced clinical events), ACUITY (acute catheterization and urgent intervention triage strategy), and HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trials

Field Value
Model ID11-026-01
Model NameMehran 2011
Pubmed ID21700252
First AuthorMehran
JournalJournal of the American College of Cardiology: Cardiovascular Interventions
Year2011
TitleImpact of bleeding on mortality after percutaneous coronary intervention results from a patient-level pooled analysis of the REPLACE-2 (randomized evaluation of PCI linking angiomax to reduced clinical events), ACUITY (acute catheterization and urgent intervention triage strategy), and HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trials
Primary Index ConditionCoronary Artery Disease (CAD)
Secondary Index ConditionRevascularization
OutcomeHemorrhage
Model Sample Size17034
Cohort Sample Size17034
Number of Events267
Follow-Up DurationShort (<3 months)
AUROC0.74
Calibration Reported1
CovariatesSerum creatinine (per 0.1 mg/dl); Age (per 5 yrs); Sex: female; Presentation: normal biomarkers (elective/ACS); Presentation: NSTEMI - raised biomarkers; Presentation: STEMI; White blood cell count (per 10^9/l); Current cigarette smoker; Randomized treatment: UFH/Enox + GPI; Randomized treatment: bivalirudin alone; Randomized treatment: bivalirudin + GPI; Intercept
Mesh TermsTo be updated
Number of Validations0

External Validations