Predictors of outcome in patients with acute coronary syndromes without persistent ST-segment elevation. Results from an international trial of 9461 patients. The PURSUIT Investigators.

Field Value
Model ID00-010-02
Model NamePlatelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin (eptifibatide) Therapy (PURSUIT) - MACE
Pubmed ID10840005
First AuthorBoersma
JournalCirculation
Year2000
TitlePredictors of outcome in patients with acute coronary syndromes without persistent ST-segment elevation. Results from an international trial of 9461 patients. The PURSUIT Investigators.
Primary Index ConditionCoronary Artery Disease (CAD)
Secondary Index ConditionAcute Coronary Syndrome (ACS)
OutcomeMACE
Model Sample Size9461
Cohort Sample Size9461
Number of Events1417
Follow-Up DurationShort (<3 months)
AUROC0.669
Calibration Reported1
CovariatesAge 50 years; Age 60 years; Age 70 years; Age 80 years; Male gender; Worst CCS-class in previous 6 weeks: III or IV; Heart rate 80 bpm; Heart rate 100 bpm; Heart rate 120 bpm; Systolic blood pressure 120 mmHg; Systolic blood pressure 100 mmHg; Systolic blood pressure 80 mmHg; Signs of heart failure (rales); ST-depression on presenting ECG
Mesh TermsTo be updated
Number of Validations4

External Validations

Yes
4
0.575
1st Author Year Sample Size AUC Calibration Relatedness
Paredes 2015 460 NR No Distantly Related
Chew 2013 1542 0.484 No Distantly Related
Paredes 2013 559 0.575 No Distantly Related
Lee 2011 4743 0.691 Yes Related