The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making

Field Value
Model ID00-012-01
Model NameThrombolysis in Myocardial Infarction (TIMI) Risk Score for non-ST-segment elevation myocardial infarction/ unstable angina (NSTEMI/UA) - Composite Endpoint
Pubmed ID10938172
First AuthorAntman
JournalJournal of the American Medical Association
Year2000
TitleThe TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making
Primary Index ConditionCoronary Artery Disease (CAD)
Secondary Index ConditionAcute Coronary Syndrome (ACS)
OutcomeMACE
Model Sample Size1957
Cohort Sample Size1957
Number of Events327
Follow-Up DurationShort (<3 months)
AUROCNR
Calibration Reported1
CovariatesAge >=65 y; At least 3 risk factors for CAD (family history of CAD, HTN, hypercholesterolemia, DM, or smoking); Significant coronary stenosis (e.g., prior coronary stenosis >=50%); ST deviation; Severe anginal symptoms (e.g., >=2 anginal events in last 24 h); Use of aspirin in last 7 days; Elevated serum cardiac markers
Mesh TermsTo be updated
Number of Validations20

External Validations

Yes
20
0.67
1st Author Year Sample Size AUC Calibration Relatedness
Chase 2006 1354 NR No Mismatch
Kim 2011 1261 NR No Distantly Related
Soiza 2005 869 NR Yes Distantly Related
Martinoni 2012 3214 NR No Mismatch
Conti 2016 589 0.56 No Distantly Related
Antman 2000 1607 0.59 Yes Distantly Related
Antman 2000 1953 0.61 Yes Closely Related
Liu 2014 564 0.621 No Distantly Related
Morrow 2002 1915 0.64 Yes Distantly Related
Antman 2000 1564 0.65 Yes Distantly Related
Huang 2014 747 0.654 No Distantly Related
Sanchis 2005 646 0.66 No Distantly Related
Bartholomew 2004 237 0.68 No Related
Chen 2016 833 0.689 No Distantly Related
Liu 2014 648 0.71 No Distantly Related
Backus 2013 2388 0.75 No Distantly Related
Lee 2011 4743 0.757 Yes Distantly Related
Tong 2005 957 0.77 No Distantly Related
Body 2009 796 0.77 No Mismatch
Tong 2014 678 0.862 No Distantly Related